Guggul E & Z 99% 75mg (60 Capsules)

Cholesterol Level Support


By enhancing bile elimination of cholesterol, guggul reduced LDL cholesterol in 80% of studies while maintaining HDL (Singh et al., 2007). Negative or inconclusive studies used low concentrations of guggulsterones (2.5% guggul was used in two studies reported in JAMA) (Szapary et al., 2003). Our product is a potent 99% extract of guggulsterones E & Z.


At least two studies have shown that guggulsterones are highly effective antagonists of the farnesoid X receptor that is an important regulator of cholesterol and bile acid homeostasis (Wu et al., 2002). The study showed guggulsterone also up-regulates the bile salt export pump responsible for removal of cholesterol metabolites and bile acids via the bile.


As reported in animal studies, guggul has a mild thyroid hormone (T3) stimulating benefit, which may require monitoring of T3 and thyroid stimulating hormone in hyperthyroid patients (Panda & Kar, 1999). Guggul has been used traditionally for the obese, favouring weight reduction.


Guggulsterone has been found to potently inhibit the activation of NF-kappaB, a critical regulator of inflammatory responses (Deng, 2007). Guggul has been used traditionally for rheumatism.


Recommended Dosage:

1 capsule twice daily for adults, while monitoring blood to keep cholesterol within normal limits.


Target Client:

For those requiring cholesterol homeostasis. Note: Innate Multivitamin, Innate Antioxidants or Grape Seed Extract, Chromium GTF, and Fish oil may be appropriate cardiovascular supports as well.


Hong Kong Compliance

Ingredients: Rice Powder, Gelatin Capsule, and Guggul Gum Extract.

SVE No.: 10-015868



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